He served in several different roles in government, and his literary skills were so well recognized that he was often asked to draft important documents while he was in Ravenna. (Why Ravenna and not Rome? That is for the next post.) Whether because he was a devoted statesman, or just because of personal inclinations, his writings try to unite the cultural differences between the Eastern and Western Roman empires, between Greek and Roman cultures, between the Roman culture and the invading Goths, and even between established Christian doctrine and heresies. After his retirement from public life, he founded a monastery and turned to writing about religion.
The immediate reason for bringing him up in a medieval blog, however, is his link to medieval universities, which didn't exist for several centuries after his death. We are familiar by now with the medieval curriculum of the trivium (Grammar, Rhetoric, Logic) and the Quadrivium (Arithmetic, Music, Geometry, Astronomy). You might be surprised to know that Cassiodorus not only listed these fields of study, in that order, but also that he derives them from the study of the Bible.
In his Expositio Psalmorum ["Explanation of the Psalms"], he interprets Psalm 18.5
"Their voice resounds through all the earth, and their words to the ends of the earth"as the teachings of the Bible being spread throughout the world, and that these teachings are the origin of secular studies. Therefore, mastering the secular arts helps bring one back to better comprehension of the Bible. This was, in fact, considered the original purpose of medieval universities: to train better clerics.