The University of Orleans started in 1230, when several; teachers and students fled the turmoil taking place at the University of Paris. Pope Clement V (1264-1314) studied there, and as pope published a papal bull in 1306, endowing the scholarly pursuits there with the status of university. In all, twelve popes granted it privileges.
In the 1300s it had as many as 5000 students from France, Germany, and even Scotland. Eustache Deschamps was one. St. Ivo of Kemartin, the patron saint of lawyers, was another. Later notables were John Calvin, Pierre de Fermat (of Fermat's Last Theorem fame), and Molière.
The current University of Orleans was founded in 1960. The original had been merged with the University of Paris in 1808.
Speaking of the University of Paris, what was the turmoil that caused teachers and students to flee to Orleans and start teaching there? We'll get into that next time.